AHCC® with BioPerine® Increases Natural Killer Cell Activity AHCC® is a proprietary compound produced by cultivation of shitake mushroom mycelia, grown in rice bran extract. Considered a superfood supplement in Japan, AHCC has been researched extensively for its immune enhancement properties. Preliminary research indicates that AHCC may significantly increase Natural Killer (NK) Cell activity. There is also evidence to suggest that AHCC may increase macrophage activity, enhance cytokine production, and support the healthy functioning of the liver as well as act as an antioxidant.AHCC® is a registered trademark of Amino Up Chemical Co., Sapporo, Japan. BioPerine® is a registered trademark and patented product of Sabinsa Corp.* 500 mg Capsule Option Available: 30, 60 Suggested Use: 2 capsules three times daily on an empty stomach. For general well-being, take 2 capsules daily.